Eric Dane, the charismatic actor beloved as Dr. Mark Sloan on Grey’s Anatomy and Cal Jacobs on Euphoria, passed away Thursday at 53, less than a year after revealing his ALS diagnosis.
The California native fought amyotrophic lateral sclerosis, the most common motor neurone disease, with courage, using his final months to raise awareness. ALS progressively paralyzes muscles, robbing patients of speech, movement, and breath; Dane shared his anger over the diagnosis on Good Morning America, haunted by his father’s suicide when he was just seven.
“With heavy hearts, we share that Eric Dane passed on Thursday afternoon following a courageous battle with ALS,” his family stated.
Surrounded by devoted wife Rebecca Gayheart – an actress and model, and daughters Billie and Georgia, “the center of his world,” Dane spent his last days with loved ones and friends.
Hollywood stars poured out tributes. Grey’s co-star Kim Raver recalled his “twinkle in his eye” and perfect comedic timing as her on-screen husband. Kevin McKidd posted, “Rest in peace buddy.” Euphoria creator Sam Levinson called working with him an honor and friendship a gift.
Dane’s career sparkled across TV and film. From Jason Dean in Charmed to Captain Tom Chandler in The Last Ship, he shone in movies like Marley & Me, Valentine’s Day, and Burlesque. Debuting in The Wonder Years (1993), the San Francisco-born talent leaves an indelible legacy.
“He will be deeply missed, and lovingly remembered always. Eric adored his fans,” his family added, thanking supporters worldwide.

